History of Kyorin Group

We have unceasingly strived to realize our corporate philosophy of always making a contribution to human health.

Kyorin will continue to take on challenges and will evolve to become a company supporting healthy lifestyles through our business in the treatment and prevention of disease and the maintenance and promotion of good health.

  • The purple border isCompany history
  • The orange border isProduct history

1923年~

1923年

(Company history)

Toyo Shinyaku Sha, the predecessor of KYORIN Pharmaceutical Co., Ltd., was founded.

1931年

(Company history)

Kyorin Chemical Laboratory was established.

1940年

(Company history)

Kyorin Chemical Laboratory was renamed KYORIN Pharmaceutical Co., Ltd., and Kyorin Yakuhin Co., Ltd. was organized as an independent marketing division.

1947年

(Company history)

The Okaya Plant was started.

1950年~

1957年

(Company history)

The medical journal bulletin “Doctor Salon” was started.

1961年

(Product history)

Behyd, a diuretic and antihypertensive agent, was launched.

1962年

(Company history)

Kyorin Chemical Laboratory (later Technical Center of Development) was established.

1965年

(Company history)

The Head Office was completed in Kanda Surugadai.

(Product history)

KYORIN AP-2, an analgesic, was launched.
Deamelin-S, an oral hypoglycemic agent, was launched.

1967年

(Company history)

The Nogi Plant was opened.

1971年

(Product history)

Cholexamin, a lipid metabolism and peripheral circulation improving agent, was launched.

1974年

(Product history)

Hespander, a plasma substitute and extracorporeal circulation flow improver, was launched.

1977年

(Company history)

Central Research Laboratories were opened.

1980年~

1980年

(Product history)

Norfloxacin (NFLX), an antibacterial agent, was licensed to Merck & Co. (U.S.A.).

1981年

(Product history)

Mucodyne, a mucoregulant, was launched.

1984年

(Product history)

Baccidal (NFLX), a broadspectrum oral antibacterial agent, was launched.

1989年

(Product history)

Ketas, for bronchial asthma and cerebrovascular disorders, was launched.
Baccidal Eyedrops, a broadspectrum ophthalmic antibacterial agent, was launched.

1992年

(Company history)

KYORIN Pharmaceutical Co., Ltd. and Kyorin Yakuhin Co., Ltd. were merged, and the new KYORIN Pharmaceutical Co., Ltd. was founded.

1993年

(Product history)

Megalocin (FLRX), a long-acting new quinolone agent, was launched.

1995年

(Company history)

The Noshiro Plant was opened.

1996年

(Company history)

A joint venture, Nisshin KYORIN Pharmaceutical Co., Ltd., was established with Kyorin’s capital participation.
The Research Center (now the WATARASE Research Center) was founded.

(Product history)

Pentasa, a treatment for ulcerative colitis and Crohn’s disease, was launched.

(Product history)

Gatifloxacin (GFLX) was licensed to Bristol-Myers Squibb (U.S.A.).

1998年

(Company history)

Milton, an effervescent disinfectant business, was acquired from P&G.

1999年

(Company history)

Listed on the Tokyo Stock Exchange, Second Section.

2000年

(Company history)

Listed on the Tokyo Stock Exchange, First Section.

(Product history)

Gatifloxacin eyedrops was licensed to Allergan (U.S.A.).

2000年~

2001年

(Company history)

A subsidiary company, Kyorin USA, Inc. (U.S.A.), was established.

(Product history)

Kipres, the leukotriene receptor antagonist and bronchial asthma treatment medicine, was launched.

2002年

(Company history)

A subsidiary company, Kyorin Europe GmbH (Germany), was established.

(Product history)

Gatiflo (GFLX), a broad-spectrum, oral antibacterial agent, was launched.

2004年

(Company history)

ActivX Biosciences, Inc. (U.S.A.) became a wholly owned subsidiary.

2005年

(Company history)

The stock of Toyo Pharma Co., Ltd. (present KYORIN Rimedio Co., Ltd.) was acquired, making it into a subsidiary company.

2006年

(Company history)

The Nogi Plant was closed.

(Company history)

The Kyorin Group shifts to a holding company structure through a share exchange with KYORIN Co., Ltd.

2007年

(Product history)

Uritos Tablets 0.1 mg, an overactive bladder drug, was launched.

2008年

(Company history)

KYORIN Pharmaceutical merged with Nissin Kyorin Pharmaceutical.

2010年

(Company history)

KYORIN Co., Ltd. changed its name to KYORIN Holdings, Inc.

2010年~

2012年

(Company history)

Acquisition (conversion into subsidiary) of the Shiga Plant of MSD K.K. and established KYORIN Pharmaceutical Facilities Co., Ltd.

(Product history)

RUBYSTA, a multi-purpose disinfectant cleaner, was launched.

2013年

(Company history)

Head office moved to Ochanomizu sola city in Kanda Surugadai.

(Product history)

Flutiform, a combination drug for asthma treatment, was launched.

2015年

(Company history)

Establishment of the WATARASE Research Center of KYORIN Pharmaceutical Co., Ltd. through consolidation of the Drug Discovery Center (the former Central Research Laboratories) and the R&D Center (the former Research Center).

(Product history)

Eklira Genuair, a treatment for COPD, was launched.
FPR2 agonist program was licensed to Bristol-Myers Squibb Company (U.S.A.)

2016年

(Company history)

The Okaya Plant was closed

(Product history)

Montelukast tablets 10mg, 5mg「KM」, the leukotriene receptor antagonist and bronchial asthma treatment medicine, was launched.
DESALEX Tablets 5mg a treatment of allergic diseases drug was launched売

2017年

(Company history)

KYORIN Rimedio Co., Ltd.’s Takaoka Pharmaceutical Technology Innovation Center was established.

2018年

(Company history)

New manufacturing subsidiary, KYORIN Pharmaceutical Group Facilities Co., Ltd. (head office: Tokyo), commences operations.

(Product history)

Beova Tablets 50mg a treatment of OAB drug was launched.

2019年

(Product history)

GeneSoC®, a microchannel-based genetic measurement device, was launched.

2020年

(Company history)

KYORIN Pharmaceutical Group Facilities Co., Ltd. and KYORIN Medical Supply Co., Ltd. merge.

(Product history)

Lasvic Tablets 75mg an oral quinolone antibacterial agent was launched.

2020年~

2021年

(Product history)

Lasvic Intravenous Drip Infusion Kit 150mg an injectable new quinolone antibacterial agent was launched.

(Product history)

Zymso Intravesical Solution 50%, an interstitial cystitis treatmet was launched.

(Product history)

GeneSoC® mini was launched.

2022年

(Product history)

Lyfnua® Tablets 45mg Selective P2X3 receptor antagonist/Refractory chronic cough was launched.

(Company history)

ActivX Biosciences, Inc. was dissolved.

2023年

(Company history)

KYORIN Holdings, Inc. changed its trade name to KYORIN Pharmaceutical Co., Ltd. through absorption type merger of KYORIN Pharmaceutical Co., Ltd.